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ERCC5 抗体 (AA 1-270)

This anti-ERCC5 antibody is a 兔 多克隆 antibody detecting ERCC5 in IF. Suitable for 人.
产品编号 ABIN1512873
发货至: 中国

Quick Overview for ERCC5 抗体 (AA 1-270) (ABIN1512873)

抗原

See all ERCC5 抗体
ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))

适用

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宿主

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克隆类型

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多克隆

标记

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This ERCC5 antibody is un-conjugated

应用范围

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Immunofluorescence (IF)
  • 抗原表位

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    AA 1-270

    序列

    MGVQGLWKLL ECSGRQVSPE ALEGKILAVD ISIWLNQALK GVRDRHGNSI ENPHLLTLFH RLCKLLFFRI RPIFVFDGDA PLLKKQTLVK RRQRKDLASS DSRKTTEKLL KTFLKRQAIK TAFRSKRDEA LPSLTQVRRE NDLYVLPPLQ EEEKHSSEEE DEKEWQERMN QKQALQEEFF HNPQAIDIES EDFSSLPPEV KHEILTDMKE FTKRRRTLFE AMPEESDDFS QYQLKGLLKK NYLNQHIEHV QKEMNQQHSG HIRRQYEDEG

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human ERCC5 (NP_000114.2).

    亚型

    IgG
  • 应用备注

    IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))

    别名

    ERCC5

    背景

    This gene encodes a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes, including RNA polymerase II transcription, and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G), which is also referred to as xeroderma pigmentosum VII (XP7), a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. Some patients also develop Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Read-through transcription exists between this gene and the neighboring upstream BIVM (basic, immunoglobulin-like variable motif containing) gene.,ERCC5,COFS3,ERCC5-201,ERCM2,UVDR,XPG,XPGC,Epigenetics & Nuclear Signaling,DNA Damage & Repair,ERCC5

    分子量

    27 kDa/47 kDa/133 kDa

    基因ID

    2073

    UniProt

    P28715

    途径

    DNA Damage Repair
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