CD46 抗体 (AA 40-320)
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- 抗原 See all CD46 抗体
- CD46
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抗原表位
- AA 40-320
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CD46 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)
- 序列
- TFEAMELIGK PKPYYEIGER VDYKCKKGYF YIPPLATHTI CDRNHTWLPV SDDACYRETC PYIRDPLNGQ AVPANGTYEF GYQMHFICNE GYYLIGEEIL YCELKGSVAI WSGKPPICEK VLCTPPPKIK NGKHTFSEVE VFEYLDAVTY SCDPAPGPDP FSLIGESTIY CGDNSVWSRA APECKVVKCR FPVVENGKQI SGFGKKFYYK ATVMFECDKG FYLDGSDTIV CDSNSTWDPP VPKCLKVSTS STTKSPASSA SGPRPTYKPP VSNYPGYPKP E
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 40-320 of human CD46 (NP_722548.1).
- 亚型
- IgG
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid freeze / thaw cycles
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- CD46
- 别名
- CD46 (CD46 产品)
- 背景
- The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.,AHUS2,MCP,MIC10,TLX,TRA2.10,CD46,Immunology & Inflammation,CD markers,Cell Intrinsic Innate Immunity Signaling Pathway,CD46
- 分子量
- 36 kDa/39 kDa/40 kDa/41 kDa/42 kDa/43 kDa/44 kDa
- 基因ID
- 4179
- UniProt
- P15529
- 途径
- Regulation of Actin Filament Polymerization
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