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ALIX 抗体 (AA 1-180)

This anti-ALIX antibody is a 兔 多克隆 antibody detecting ALIX in WB 和 IF. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN1512565
发货至: 中国

Quick Overview for ALIX 抗体 (AA 1-180) (ABIN1512565)

抗原

See all ALIX (PDCD6IP) 抗体
ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))

适用

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宿主

  • 70
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克隆类型

  • 60
  • 24
多克隆

标记

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This ALIX antibody is un-conjugated

应用范围

  • 56
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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 15
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    • 2
    • 2
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    • 1
    • 1
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    AA 1-180

    序列

    MATFISVQLK KTSEVDLAKP LVKFIQQTYP SGGEEQAQYC RAAEELSKLR RAAVGRPLDK HEGALETLLR YYDQICSIEP KFPFSENQIC LTFTWKDAFD KGSLFGGSVK LALASLGYEK SCVLFNCAAL ASQIAAEQNL DNDEGLKIAA KHYQFASGAF LHIKETVLSA LSREPTVDIS

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human ALIX / PDCD6IP (NP_037506.2).

    亚型

    IgG
  • 应用备注

    WB,1:200 - 1:2000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Bei, Xu, Lv, Yu, Xu, Che, Das, Tigges, Toxavidis, Ghiran, Shah, Li, Zhang, Das, Xiao: "Exercise-induced circulating extracellular vesicles protect against cardiac ischemia-reperfusion injury." in: Basic research in cardiology, Vol. 112, Issue 4, pp. 38, (2018) (PubMed).

    Xu, Qin, An, Tang, Huang, Zheng: "MiR-145 detection in urinary extracellular vesicles increase diagnostic efficiency of prostate cancer based on hydrostatic filtration dialysis method." in: The Prostate, Vol. 77, Issue 10, pp. 1167-1175, (2017) (PubMed).

    Zhao, Wu, Duan, Ma, Shen, Wei, Cui, Zhang, Xie, Liu: "Quantitative proteomic analysis of exosome protein content changes induced by hepatitis B virus in Huh-7 cells using SILAC labeling and LC-MS/MS." in: Journal of proteome research, Vol. 13, Issue 12, pp. 5391-402, (2015) (PubMed).

  • 抗原

    ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))

    别名

    PDCD6IP

    背景

    This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15.,PDCD6IP,AIP1,ALIX,DRIP4,HP95,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,PDCD6IP

    分子量

    30 kDa/96 kDa

    基因ID

    10015

    UniProt

    Q8WUM4

    途径

    p53 Pathway, EGFR Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Tube Formation
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