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PLAT 抗体 (AA 38-87)

The 兔 多克隆 anti-PLAT antibody (ABIN1454007) specifically detects PLAT in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1454007
发货至: 中国
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Quick Overview for PLAT 抗体 (AA 38-87) (ABIN1454007)

抗原

See all PLAT 抗体
PLAT (Plasminogen Activator, Tissue (PLAT))

适用

  • 144
  • 61
  • 54
  • 7
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  • 2
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  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 138
  • 19
  • 13
  • 1
  • 1
兔

克隆类型

  • 135
  • 36
多克隆

标记

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  • 3
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  • 2
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  • 1
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This PLAT antibody is un-conjugated

应用范围

  • 132
  • 61
  • 51
  • 26
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  • 21
  • 20
  • 17
  • 10
  • 10
  • 6
  • 4
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Western Blotting (WB), ELISA
  • 抗原表位

    • 15
    • 15
    • 14
    • 13
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
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    • 1
    • 1
    • 1
    • 1
    AA 38-87

    原理

    tPA Antibody

    特异性

    TPA Polyclonal Antibody detects endogenous levels of tPA protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from human tPA. AA range:38-87

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    PLAT (Plasminogen Activator, Tissue (PLAT))

    别名

    tPA

    背景

    Synonyms: PLAT, Tissue-type plasminogen activator, t-PA, t-plasminogen activator, tPA, Alteplase, Reteplase

    Background: This gene encodes tissue-type plasminogen activator, a secreted serine protease that converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. The encoded preproprotein is proteolytically processed by plasmin or trypsin to generate heavy and light chains. These chains associate via disulfide linkages to form the heterodimeric enzyme. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, while decreased activity leads to hypofibrinolysis, which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016],

    Gene Name: PLAT

    Protein Name: Tissue-type plasminogen activator

    分子量

    62 kDa

    基因ID

    5327

    OMIM

    173370

    UniProt

    P00750

    途径

    Autophagy, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, SARS-CoV-2 Protein Interactome
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