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SOCS1 抗体 (AA 49-98)

The 兔 多克隆 anti-SOCS1 antibody (ABIN1453935) specifically detects SOCS1 in WB, ELISA, IHC 和 IF. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1453935
发货至: 中国
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Quick Overview for SOCS1 抗体 (AA 49-98) (ABIN1453935)

抗原

See all SOCS1 抗体
SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))

适用

  • 59
  • 42
  • 39
  • 6
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
人, 小鼠, 大鼠

宿主

  • 57
  • 3
  • 2
兔

克隆类型

  • 61
  • 1
多克隆

标记

  • 33
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
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This SOCS1 antibody is un-conjugated

应用范围

  • 47
  • 28
  • 21
  • 10
  • 8
  • 8
  • 5
  • 4
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 11
    • 9
    • 8
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 49-98

    原理

    SOCS-1 Antibody

    特异性

    SOCS-1 Polyclonal Antibody detects endogenous levels of SOCS-1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from human SOCS-1. AA range:49-98

    亚型

    IgG
  • 应用备注

    IF 1:50-200 WB 1:500-2000, ELISA 1:10000-20000 IHC 1:50-300

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))

    别名

    SOCS-1

    背景

    Synonyms: SOCS1, SSI1, TIP3, Suppressor of cytokine signaling 1, SOCS-1, JAK-binding protein, JAB, STAT-induced STAT inhibitor 1, SSI-1, Tec-interacting protein 3, TIP-3

    Background: This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma.The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq, Jul 2008],

    Gene Name: SOCS1

    Protein Name: Suppressor of cytokine signaling 1

    分子量

    23 kDa

    基因ID

    8651

    OMIM

    603597

    UniProt

    O15524

    途径

    JAK/STAT Signaling, Interferon-gamma Pathway, TLR signaling, Response to Growth Hormone Stimulus
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