CXCL12 抗体 (AA 44-93)
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Quick Overview for CXCL12 抗体 (AA 44-93) (ABIN1453896)
抗原
See all CXCL12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 44-93
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原理
- SDF-1 Antibody
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特异性
- SDF-1 Polyclonal Antibody detects endogenous levels of SDF-1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human SDF-1. AA range:44-93
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亚型
- IgG
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应用备注
- IF 1:50-200 WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))
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别名
- SDF-1
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背景
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Synonyms: CXCL12, SDF1, SDF1A, SDF1B, Stromal cell-derived factor 1, SDF-1, hSDF-1, C-X-C motif chemokine 12, Intercrine reduced in hepatomas, IRH, hIRH, Pre-B cell growth-stimulating factor, PBSF
Background: C-X-C motif chemokine ligand 12(CXCL12) Homo sapiens This antimicrobial gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. The encoded protein functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014],
Gene Name: CXCL12
Protein Name: Stromal cell-derived factor 1
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分子量
- 10 kDa
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基因ID
- 6387
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OMIM
- 600835
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UniProt
- P48061
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途径
- Regulation of Cell Size, CXCR4-mediated Signaling Events, Negative Regulation of intrinsic apoptotic Signaling
抗原
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