RUNX3 抗体 (AA 133-182)
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北京 101111
Quick Overview for RUNX3 抗体 (AA 133-182) (ABIN1453878)
抗原
See all RUNX3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 133-182
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原理
- RUNX3 Antibody
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特异性
- RUNX3 Polyclonal Antibody detects endogenous levels of RUNX3 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human RUNX3. AA range:133-182
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))
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别名
- RUNX3
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背景
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Synonyms: RUNX3; AML2; CBFA3; PEBP2A3; Runt-related transcription factor 3; Acute myeloid leukemia 2 protein; Core-binding factor subunit alpha-3; CBF-alpha-3; Oncogene AML-2; Polyomavirus enhancer-binding protein 2 alpha C subunit; PEA2-alpha C; PEB
Background: This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],
Gene Name: RUNX3
Protein Name: Runt-related transcription factor 3
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分子量
- 44 kDa
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基因ID
- 864
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OMIM
- 600210
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UniProt
- Q13761
抗原
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