PUMA 抗体 (AA 120-169)
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北京 101111
Quick Overview for PUMA 抗体 (AA 120-169) (ABIN1453833)
抗原
See all PUMA (BBC3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 120-169
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原理
- PUMA Antibody
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特异性
- PUMA Polyclonal Antibody detects endogenous levels of PUMA protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human PUMA. AA range:120-169
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亚型
- IgG
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anti-BCL2 Binding Component 3 (BBC3) (AA 131-180) antibody
BBC3 适用: 人 WB, FACS, IP, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-BCL2 Binding Component 3 (BBC3) (AA 119-154) antibodyBBC3 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB01353 unconjugated
anti-BCL2 Binding Component 3 (BBC3) (AA 119-154) antibodyBBC3 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-BCL2 Binding Component 3 (BBC3) (AA 109-137) antibodyBBC3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB33714 unconjugated
anti-BCL2 Binding Component 3 (BBC3) (N-Term) antibodyBBC3 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-BCL2 Binding Component 3 (BBC3) (AA 186-199) antibodyBBC3 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-BCL2 Binding Component 3 (BBC3) (C-Term) antibodyBBC3 适用: 人, 小鼠 WB, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-BCL2 Binding Component 3 (BBC3) antibodyBBC3 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB1935 unconjugated Recombinant Antibody
anti-BCL2 Binding Component 3 (BBC3) (AA 2-16) antibodyBBC3 适用: 人, 大鼠, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-BCL2 Binding Component 3 (BBC3) (AA 98-152) antibodyBBC3 适用: 人 ELISA 宿主: 小鼠 Monoclonal 5D10 unconjugated
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应用备注
- WB 1:500-2000 IF 1:100-300 ELISA 1:5000-20000 Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
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别名
- PUMA
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背景
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Synonyms: BBC3, PUMA, Bcl-2-binding component 3, JFY-1, p53 up-regulated modulator of apoptosis
Background: This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011],
Gene Name: BBC3
Protein Name: Bcl-2-binding component 3
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分子量
- 20 kDa
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基因ID
- 27113
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OMIM
- 605854
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UniProt
- Q9BXH1
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途径
- p53 Pathway, Positive Regulation of Endopeptidase Activity
抗原
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