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PFKM 抗体 (AA 320-369)

The 兔 多克隆 anti-PFKM antibody (ABIN1453764) specifically detects PFKM in WB, IHC, ELISA 和 IF. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1453764
发货至: 中国
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Quick Overview for PFKM 抗体 (AA 320-369) (ABIN1453764)

抗原

See all PFKM 抗体
PFKM (phosphofructokinase, Muscle (PFKM))

适用

  • 104
  • 59
  • 56
  • 9
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 96
  • 10
  • 4
  • 4
兔

克隆类型

  • 76
  • 38
多克隆

标记

  • 54
  • 11
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
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This PFKM antibody is un-conjugated

应用范围

  • 94
  • 48
  • 46
  • 44
  • 25
  • 15
  • 11
  • 10
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
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  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 13
    • 9
    • 8
    • 6
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 320-369

    原理

    PFKM Antibody

    特异性

    PFKM Polyclonal Antibody detects endogenous levels of PFKM protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from human PFK-1. AA range:320-369

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    PFKM (phosphofructokinase, Muscle (PFKM))

    别名

    PFK-1

    背景

    Synonyms: PFKM, PFKX, 6-phosphofructokinase, muscle type, Phosphofructo-1-kinase isozyme A, PFK-A, Phosphofructokinase-M, Phosphofructokinase 1, Phosphohexokinase

    Background: Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type.This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.[provided by RefSeq, Nov 2009],

    Gene Name: PFKM

    Protein Name: 6-phosphofructokinase muscle type

    分子量

    85 kDa

    基因ID

    5213

    OMIM

    610681

    UniProt

    P08237

    途径

    Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Warburg Effect
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