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PGC 抗体 (AA 257-306)

The 兔 多克隆 anti-PGC antibody (ABIN1453761) specifically detects PGC in WB, IHC, ELISA 和 IF. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN1453761
发货至: 中国
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Quick Overview for PGC 抗体 (AA 257-306) (ABIN1453761)

抗原

See all PGC 抗体
PGC (Pepsinogen C (PGC))

适用

  • 92
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人, 大鼠, 小鼠

宿主

  • 84
  • 26
  • 2
兔

克隆类型

  • 88
  • 24
多克隆

标记

  • 43
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This PGC antibody is un-conjugated

应用范围

  • 67
  • 36
  • 34
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  • 7
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  • 5
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 13
    • 6
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    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 257-306

    原理

    Pepsin C Antibody

    特异性

    Pepsin C Polyclonal Antibody detects endogenous levels of Pepsin C protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from human Pepsin C. AA range:257-306

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    PGC (Pepsinogen C (PGC))

    别名

    Pepsin C

    背景

    Synonyms: PGC, Gastricsin, Pepsinogen C

    Background: This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009],

    Gene Name: PGC

    Protein Name: Gastricsin

    分子量

    42 kDa

    基因ID

    5225

    OMIM

    169740

    UniProt

    P20142
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