OCRL 抗体 (AA 150-199)
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北京 101111
Quick Overview for OCRL 抗体 (AA 150-199) (ABIN1453701)
抗原
See all OCRL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 150-199
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原理
- OCRL Antibody
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特异性
- OCRL Polyclonal Antibody detects endogenous levels of OCRL protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human OCRL. AA range:150-199
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))
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别名
- OCRL
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背景
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Synonyms: OCRL, INPP5F, OCRL1, Inositol polyphosphate 5-phosphatase OCRL-1, Lowe oculocerebrorenal syndrome protein
Background: This gene encodes an inositol polyphosphate 5-phosphatase. This protein is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and, endosomes and the plasma membrane. This protein may also play a role in primary cilium formation. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],
Gene Name: OCRL
Protein Name: Inositol polyphosphate 5-phosphatase OCRL-1
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分子量
- 104 kDa
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基因ID
- 4952
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OMIM
- 300535
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UniProt
- Q01968
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途径
- Inositol Metabolic Process
抗原
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