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OCRL 抗体 (Internal Region)

This 兔 多克隆 antibody specifically detects OCRL in WB 和 ELISA. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN7216158
发货至: 中国
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Quick Overview for OCRL 抗体 (Internal Region) (ABIN7216158)

抗原

See all OCRL 抗体
OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))

适用

  • 21
  • 4
  • 1
  • 1
人, 小鼠

宿主

  • 15
  • 7

克隆类型

  • 18
  • 4
多克隆

标记

  • 18
  • 2
  • 1
  • 1
This OCRL antibody is un-conjugated

应用范围

  • 17
  • 12
  • 7
  • 4
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region

    原理

    Rabbit Anti-OCRL Polyclonal Antibody

    特异性

    OCRL Polyclonal Antibody detects endogenous levels of OCRL protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from the Internal region of human OCRL

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))

    别名

    OCRL

    背景

    OCRL, INPP5F, OCRL1, Inositol polyphosphate 5-phosphatase OCRL-1, Lowe oculocerebrorenal syndrome proteinOCRL encodes an inositol polyphosphate 5-phosphatase. OCRL, inositol polyphosphate-5-phosphatase is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and, endosomes and the plasma membrane. OCRL, inositol polyphosphate-5-phosphatase may also play a role in primary cilium formation. Mutations in OCRL cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants.

    分子量

    104kD

    基因ID

    4952

    UniProt

    Q01968

    途径

    Inositol Metabolic Process
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