OXT 抗体 (AA 40-89)
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北京 101111
Quick Overview for OXT 抗体 (AA 40-89) (ABIN1453629)
抗原
See all OXT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 40-89
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原理
- Neurophysin I Antibody
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特异性
- Neurophysin I Polyclonal Antibody detects endogenous levels of Neurophysin I protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human Neurophysin I. AA range:40-89
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- OXT (Oxytocin, Prepropeptide (OXT))
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别名
- Neurophysin I
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背景
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Synonyms: OXT, OT, Oxytocin-neurophysin 1, OT-NPI
Background: This gene encodes a precursor protein that is processed to produce oxytocin and neurophysin I. Oxytocin is a posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. [provided by RefSeq, Dec 2013],
Gene Name: OXT
Protein Name: Oxytocin-neurophysin 1
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分子量
- 12 kDa
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基因ID
- 5020
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OMIM
- 167050
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UniProt
- P01178
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途径
- Myometrial Relaxation and Contraction, Feeding Behaviour
抗原
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