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IDH2 抗体

The 兔 多克隆 anti-IDH2 antibody (ABIN1453428) specifically detects IDH2 in WB, IHC 和 IF. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1453428
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IDH2 抗体 (ABIN1453428)

抗原

See all IDH2 抗体
IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))

适用

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人, 小鼠, 大鼠

宿主

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兔

克隆类型

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多克隆

标记

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This IDH2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 原理

    IDHP Antibody

    特异性

    This antibody detects endogenous levels of human IDHP

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from human IDHP

    亚型

    IgG
  • 应用备注

    IHC 1:50-200, WB 1:500-2000. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))

    别名

    IDH2

    背景

    Synonyms: Isocitrate dehydrogenase [NADP], mitochondrial (IDH, EC 1.1.1.42, ICD-M, IDP, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase)

    Background: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer.The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants. [provided by Ref

    Gene Name: IDH2

    Protein Name: IDHP

    分子量

    50 kDa

    基因ID

    3418

    OMIM

    147650

    UniProt

    P48735

    途径

    Warburg Effect
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