Cathepsin B 抗体 (AA 168-217)
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Quick Overview for Cathepsin B 抗体 (AA 168-217) (ABIN1453029)
抗原
See all Cathepsin B (CTSB) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 168-217
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原理
- Cathepsin B Antibody
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特异性
- Cathepsin B Polyclonal Antibody detects endogenous levels of Cathepsin B protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human Cathepsin B. AA range:168-217
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亚型
- IgG
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anti-Cathepsin B (CTSB) (AA 1-339) antibody
CTSB 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin B (CTSB) (AA 251-339), (Heavy Chain) antibodyCTSB 适用: 小鼠 WB, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin B (CTSB) (AA 82-333) antibodyCTSB 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin B (CTSB) (AA 42-339) antibodyCTSB 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin B (CTSB) antibodyCTSB 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Cathepsin B (CTSB) antibodyKD Validated CTSB 适用: 人 WB 宿主: 兔 Monoclonal 23GB1130 unconjugated Recombinant Antibody
anti-Cathepsin B (CTSB) (AA 1-339) antibodyCTSB 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cathepsin B (CTSB) (AA 129-333) antibodyCTSB 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin B (CTSB) (AA 129-333) antibodyCTSB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Cathepsin B (CTSB)
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别名
- Cathepsin B
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背景
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Synonyms: CTSB; CPSB; Cathepsin B; APP secretase; APPS; Cathepsin B1
Background: This gene encodes a member of the C1 family of peptidases. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to form the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer's disease, the most common cause of dementia. Overexpression of the encoded protein has been associated with esophageal adenocarcinoma and other tumors.
Gene Name: CTSB
Protein Name: Cathepsin B
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分子量
- 37 kDa
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基因ID
- 1508
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OMIM
- 116810
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UniProt
- P07858
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途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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