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ABI1 抗体 (AA 152-201)

The 兔 多克隆 anti-ABI1 antibody (ABIN1452867) specifically detects ABI1 in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1452867
发货至: 中国
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Quick Overview for ABI1 抗体 (AA 152-201) (ABIN1452867)

抗原

See all ABI1 抗体
ABI1 (Abl-Interactor 1 (ABI1))

适用

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人, 小鼠, 大鼠

宿主

  • 88
  • 2
兔

克隆类型

  • 88
  • 2
多克隆

标记

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  • 5
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This ABI1 antibody is un-conjugated

应用范围

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  • 13
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  • 1
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Western Blotting (WB), ELISA
  • 抗原表位

    • 22
    • 17
    • 15
    • 8
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
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    AA 152-201

    原理

    Abi-1 Antibody

    特异性

    Abi-1 Polyclonal Antibody detects endogenous levels of Abi-1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from human Abi-1. AA range:152-201

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    ABI1 (Abl-Interactor 1 (ABI1))

    别名

    Abi-1

    背景

    Synonyms: ABI1, SSH3BP1, Abl interactor 1, Abelson interactor 1, Abi-1, Abl-binding protein 4, AblBP4, Eps8 SH3 domain-binding protein, Eps8-binding protein, Nap1-binding protein, Nap1BP, Spectrin SH3 domain-binding protein 1, e3B1

    Background: This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10,11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14. [provided by RefSeq

    Gene Name: ABI1

    Protein Name: Abl interactor 1

    分子量

    55 kDa

    基因ID

    10006

    OMIM

    603050

    UniProt

    Q8IZP0

    途径

    RTK signaling, Response to Water Deprivation, ER-Nucleus Signaling
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