ANAPC5 抗体 (AA 151-200)
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Quick Overview for ANAPC5 抗体 (AA 151-200) (ABIN1452003)
抗原
See all ANAPC5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 151-200
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原理
- APC5 Antibody
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特异性
- APC5 Polyclonal Antibody detects endogenous levels of APC5 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human ANAPC5. AA range:151-200
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))
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别名
- ANAPC5
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背景
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Synonyms: ANAPC5, APC5, Anaphase-promoting complex subunit 5, APC5, Cyclosome subunit 5
Background: This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. [provided by RefSeq, Nov 2008],
Gene Name: ANAPC5
Protein Name: Anaphase-promoting complex subunit 5
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分子量
- 85 kDa
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基因ID
- 51433
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OMIM
- 606948
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UniProt
- Q9UJX4
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途径
- M Phase
抗原
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