NKX2-8 抗体 (AA 20-69)
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北京 101111
Quick Overview for NKX2-8 抗体 (AA 20-69) (ABIN1451871)
抗原
See all NKX2-8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 20-69
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原理
- Nkx-2.8 Antibody
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特异性
- Nkx-2.8 Polyclonal Antibody detects endogenous levels of Nkx-2.8 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human NKX28. AA range:20-69
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- NKX2-8 (NK2 Homeobox 8 (NKX2-8))
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别名
- NKX28
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背景
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Background: The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects. [provided by RefSeq, Dec 2015],
Gene Name: NKX2-8
Protein Name: Homeobox protein Nkx-2.8
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分子量
- 25 kDa
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基因ID
- 26257
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OMIM
- 603245
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UniProt
- Q8IUT7
抗原
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