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RGS14 抗体 (AA 125-174)

The 兔 多克隆 anti-RGS14 antibody (ABIN1451538) specifically detects RGS14 in WB, ELISA 和 IHC. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN1451538
发货至: 中国
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Quick Overview for RGS14 抗体 (AA 125-174) (ABIN1451538)

抗原

See all RGS14 抗体
RGS14 (Regulator of G-Protein Signaling 14 (RGS14))

适用

  • 69
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人, 大鼠, 小鼠

宿主

  • 66
  • 17
  • 1
兔

克隆类型

  • 69
  • 15
多克隆

标记

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This RGS14 antibody is un-conjugated

应用范围

  • 64
  • 23
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  • 14
  • 13
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  • 8
  • 5
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 15
    • 13
    • 7
    • 3
    • 3
    • 3
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    • 1
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    AA 125-174

    原理

    RGS14 Antibody

    特异性

    RGS14 Polyclonal Antibody detects endogenous levels of RGS14 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from human RGS14. AA range:125-174

    亚型

    IgG
  • 应用备注

    WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    RGS14 (Regulator of G-Protein Signaling 14 (RGS14))

    别名

    RGS14

    背景

    Synonyms: RGS14, Regulator of G-protein signaling 14, RGS14

    Background: This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008],

    Gene Name: RGS14

    Protein Name: Regulator of G-protein signaling 14

    分子量

    64 kDa

    基因ID

    10636

    OMIM

    602513

    UniProt

    O43566

    途径

    Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Platelet-derived growth Factor Receptor Signaling
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