PPP1R16A 抗体 (AA 362-411)
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Quick Overview for PPP1R16A 抗体 (AA 362-411) (ABIN1451469)
抗原
See all PPP1R16A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 362-411
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原理
- MYPT3 Antibody
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特异性
- MYPT3 Polyclonal Antibody detects endogenous levels of MYPT3 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human PPP1R16A. AA range:362-411
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亚型
- IgG
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应用备注
- WB 1:500-2000, IF ICC 1:50-200,ELISA 1:2000-20000,IHC 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- PPP1R16A (Protein Phosphatase 1, Regulatory Subunit 16A (PPP1R16A))
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别名
- PPP1R16A
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背景
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Synonyms: PPP1R16A, MYPT3, Protein phosphatase 1 regulatory subunit 16A, Myosin phosphatase-targeting subunit 3
Background: Myosin light chain kinase and phosphatase (MLCP) complexes control the phosphorylation states of regulatory myosin light chains, which is crucial for muscle and intracellular movement. MLCPs typically contain a catalytic protein phosphatase 1 (PP1c) subunit, a myosin phosphatase targeting (MYPT) subunit, and another smaller subunit.The protein encoded by this gene represents an MYPT subunit, which is responsible for directing PP1c to its intended targets. However, while other MYPTs result in PP1c activation after becoming phosphorylated, the encoded protein is phosphorylated by protein kinase A and then inhibits the catalytic activity of PP1c. [provided by RefSeq, Jul 2016],
Gene Name: PPP1R16A
Protein Name: Protein phosphatase 1 regulatory subunit 16A
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分子量
- 57 kDa
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基因ID
- 84988
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OMIM
- 609172
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UniProt
- Q96I34
抗原
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