PPP1R16A 抗体 (AA 340-420)
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Quick Overview for PPP1R16A 抗体 (AA 340-420) (ABIN7225488)
抗原
See all PPP1R16A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 340-420
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原理
- Rabbit Anti-MYPT3 Polyclonal Antibody
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特异性
- MYPT3 Polyclonal Antibody detects endogenous levels of MYPT3 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the Internal region of human MYPT3 at AA range: 340-420
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亚型
- IgG
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anti-Protein Phosphatase 1, Regulatory Subunit 16A (PPP1R16A) (AA 1-528) antibody
PPP1R16A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 16A (PPP1R16A) (AA 429-528) antibodyPPP1R16A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B12 unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 16A (PPP1R16A) (Center) antibodyPPP1R16A 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 16A (PPP1R16A) (Internal Region) antibodyPPP1R16A 适用: 人, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 16A (PPP1R16A) antibodyPPP1R16A 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IF/ICC1:50-200,ELISA 1:2000-20000,IHC 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- PPP1R16A (Protein Phosphatase 1, Regulatory Subunit 16A (PPP1R16A))
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别名
- MYPT3
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背景
- PPP1R16A, MYPT3, Protein phosphatase 1 regulatory subunit 16A, Myosin phosphatase-targeting subunit 3Myosin light chain kinase and phosphatase (MLCP) complexes control the phosphorylation states of regulatory myosin light chains, which is crucial for muscle and intracellular movement. MLCPs typically contain a catalytic protein phosphatase 1 (PP1c) subunit, a myosin phosphatase targeting (MYPT) subunit, and another smaller subunit. The protein encoded by MYPT3 (protein phosphatase 1 regulatory subunit 16A, PPP1R16A) represents an MYPT subunit, which is responsible for directing PP1c to its intended targets. However, while other MYPTs result in PP1c activation after becoming phosphorylated, the encoded protein is phosphorylated by protein kinase A and then inhibits the catalytic activity of PP1c.
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分子量
- 60kD
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基因ID
- 84988
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UniProt
- Q96I34
抗原
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