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TdT 抗体 (AA 381-430)

The 兔 多克隆 anti-TdT antibody (ABIN1451214) specifically detects TdT in WB, ELISA, IHC 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN1451214
发货至: 中国
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Quick Overview for TdT 抗体 (AA 381-430) (ABIN1451214)

抗原

See all TdT (DNTT) 抗体
TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))

适用

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人

宿主

  • 98
  • 23
兔

克隆类型

  • 71
  • 49
  • 1
多克隆

标记

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This TdT antibody is un-conjugated

应用范围

  • 77
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  • 1
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 15
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    AA 381-430

    原理

    TdT Antibody

    特异性

    TdT Polyclonal Antibody detects endogenous levels of TdT protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from human DNTT. AA range:381-430

    亚型

    IgG
  • 应用备注

    IHC: 100-300.WB 1:500 - 1:2000. ELISA: 1:40000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))

    别名

    DNTT

    背景

    Synonyms: DNTT; TDT; DNA nucleotidylexotransferase; Terminal addition enzyme; Terminal deoxynucleotidyltransferase; Terminal transferase

    Background: This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008],

    Gene Name: DNTT

    Protein Name: DNA nucleotidylexotransferase

    分子量

    58 kDa

    基因ID

    1791

    OMIM

    187410

    UniProt

    P04053

    途径

    DNA Damage Repair
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