Complement Factor I 抗体 (AA 441-490)
Our Local Distributor
北京 101111
Quick Overview for Complement Factor I 抗体 (AA 441-490) (ABIN1451187)
抗原
See all Complement Factor I (CFI) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 441-490
-
原理
- Factor I Antibody
-
特异性
- Factor I Polyclonal Antibody detects endogenous levels of Factor I protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- The antiserum was produced against synthesized peptide derived from human CFI. AA range:441-490
-
亚型
- IgG
-
-
anti-Complement Factor I (CFI) (AA 358-603) antibody
CFI 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 28-243) antibodyCFI 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 19-118) antibodyCFI 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B3 unconjugated
anti-Complement Factor I (CFI) (AA 239-316) antibodyCFI 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 1-377) antibodyCFI 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 19-220) antibodyCFI 适用: 人, 大鼠 WB, IHC, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 145-194) antibodyCFI 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 19-300) antibodyCFI 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 340-583) antibodyCFI 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 1-377) antibodyCFI 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB 1:500-2000. ELISA: 1:10000. Not yet tested in other applications.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- Complement Factor I (CFI)
-
别名
- CFI
-
背景
-
Synonyms: CFI, IF, Complement factor I, C3B/C4B inactivator
Background: This gene encodes a serine proteinase that is essential for regulating the complement cascade. The encoded preproprotein is cleaved to produce both heavy and light chains, which are linked by disulfide bonds to form a heterodimeric glycoprotein. This heterodimer can cleave and inactivate the complement components C4b and C3b, and it prevents the assembly of the C3 and C5 convertase enzymes. Defects in this gene cause complement factor I deficiency, an autosomal recessive disease associated with a susceptibility to pyogenic infections. Mutations in this gene have been associated with a predisposition to atypical hemolytic uremic syndrome, a disease characterized by acute renal failure, microangiopathic hemolytic anemia and thrombocytopenia. Primary glomerulonephritis with immune deposits and age-related macular degeneration are other conditions associated with mutations of this gene. [provided by Ref
Gene Name: CFI
Protein Name: Complement factor I
-
分子量
- 65 kDa
-
基因ID
- 3426
-
OMIM
- 217030
-
UniProt
- P05156
-
途径
- Complement System
抗原
-
