CDC23 抗体 (AA 251-300)
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北京 101111
Quick Overview for CDC23 抗体 (AA 251-300) (ABIN1450935)
抗原
See all CDC23 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 251-300
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原理
- Cdc23 Antibody
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特异性
- Cdc23 Polyclonal Antibody detects endogenous levels of Cdc23 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human APC8. AA range:251-300
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- CDC23 (Cell Division Cycle 23 (CDC23))
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别名
- APC8
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背景
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Synonyms: CDC23, ANAPC8, Cell division cycle protein 23 homolog, Anaphase-promoting complex subunit 8, APC8, Cyclosome subunit 8
Background: The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. [provided by RefSeq, Jul 2008],
Gene Name: CDC23
Protein Name: Cell division cycle protein 23 homolog
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分子量
- 68 kDa
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基因ID
- 8697
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OMIM
- 603462
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UniProt
- Q9UJX2
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途径
- Protein targeting to Nucleus
抗原
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