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NXF1 抗体 (AA 1-50)

The 兔 多克隆 anti-NXF1 antibody (ABIN1450884) specifically detects NXF1 in WB 和 ELISA. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN1450884
发货至: 中国
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Quick Overview for NXF1 抗体 (AA 1-50) (ABIN1450884)

抗原

See all NXF1 抗体
NXF1 (Nuclear RNA Export Factor 1 (NXF1))

适用

  • 70
  • 10
  • 7
  • 7
  • 5
  • 4
  • 3
  • 3
  • 2
人, 大鼠, 小鼠

宿主

  • 71
  • 1
兔

克隆类型

  • 51
  • 21
多克隆

标记

  • 41
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
This NXF1 antibody is un-conjugated

应用范围

  • 53
  • 28
  • 21
  • 21
  • 19
  • 17
  • 4
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 10
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-50

    原理

    TAP Antibody

    特异性

    TAP Polyclonal Antibody detects endogenous levels of TAP protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from human NXF1. AA range:1-50

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    NXF1 (Nuclear RNA Export Factor 1 (NXF1))

    别名

    NXF1

    背景

    Synonyms: NXF1, TAP, Nuclear RNA export factor 1, Tip-associated protein, Tip-associating protein, mRNA export factor TAP

    Background: This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses. Alternative splicing results

    Gene Name: NXF1

    Protein Name: Nuclear RNA export factor 1

    分子量

    70 kDa

    基因ID

    10482

    OMIM

    602647

    UniProt

    Q9UBU9
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