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TBK1 抗体 (AA 138-187)

The 兔 多克隆 anti-TBK1 antibody (ABIN1450668) specifically detects TBK1 in ELISA, IHC 和 IF. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN1450668
发货至: 中国
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Quick Overview for TBK1 抗体 (AA 138-187) (ABIN1450668)

抗原

See all TBK1 抗体
TBK1 (TANK-Binding Kinase 1 (TBK1))

适用

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人, 小鼠

宿主

  • 121
  • 4
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兔

克隆类型

  • 97
  • 29
多克隆

标记

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This TBK1 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 138-187

    原理

    TBK1 Antibody

    特异性

    TBK1 Polyclonal Antibody detects endogenous levels of TBK1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from human TBK1. AA range:138-187

    亚型

    IgG
  • 应用备注

    IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    TBK1 (TANK-Binding Kinase 1 (TBK1))

    别名

    TBK1

    背景

    Synonyms: TBK1, NAK, Serine/threonine-protein kinase TBK1, NF-kappa-B-activating kinase, T2K, TANK-binding kinase 1

    Background: The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex.The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. [provided by RefSeq, Oct 2010],

    Gene Name: TBK1

    Protein Name: Serine/threonine-protein kinase TBK1

    分子量

    83 kDa

    基因ID

    29110

    OMIM

    604834

    UniProt

    Q9UHD2

    途径

    TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome
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