TBK1 抗体 (AA 138-187)
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北京 101111
Quick Overview for TBK1 抗体 (AA 138-187) (ABIN1450668)
抗原
See all TBK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 138-187
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原理
- TBK1 Antibody
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特异性
- TBK1 Polyclonal Antibody detects endogenous levels of TBK1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human TBK1. AA range:138-187
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亚型
- IgG
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应用备注
- IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- TBK1 (TANK-Binding Kinase 1 (TBK1))
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别名
- TBK1
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背景
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Synonyms: TBK1, NAK, Serine/threonine-protein kinase TBK1, NF-kappa-B-activating kinase, T2K, TANK-binding kinase 1
Background: The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex.The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. [provided by RefSeq, Oct 2010],
Gene Name: TBK1
Protein Name: Serine/threonine-protein kinase TBK1
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分子量
- 83 kDa
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基因ID
- 29110
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OMIM
- 604834
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UniProt
- Q9UHD2
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途径
- TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome
抗原
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