HDAC7 抗体 (pSer155)
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Quick Overview for HDAC7 抗体 (pSer155) (ABIN1450530)
抗原
See all HDAC7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 121-170, pSer155
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原理
- HDAC7 (phospho Ser155) Antibody
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特异性
- Phospho-HDAC7 (S155) Polyclonal Antibody detects endogenous levels of HDAC7 protein only when phosphorylated at S155.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human HDAC7A around the phosphorylation site of Ser155. AA range:121-170
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- HDAC7 (Histone Deacetylase 7 (HDAC7))
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别名
- HDAC7A
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背景
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Synonyms: HDAC7, HDAC7A, Histone deacetylase 7, HD7, Histone deacetylase 7A, HD7a
Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA.The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Gene Name: HDAC7
Protein Name: Histone deacetylase 7
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分子量
- 102 kDa
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基因ID
- 51564
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OMIM
- 606542
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UniProt
- Q8WUI4
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途径
- Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development
抗原
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