STK39 抗体 (pSer311)
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北京 101111
Quick Overview for STK39 抗体 (pSer311) (ABIN1450455)
抗原
See all STK39 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 277-326, pSer311
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原理
- SPAK (phospho Ser309) Antibody
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特异性
- Phospho-SPAK (S311) Polyclonal Antibody detects endogenous levels of SPAK protein only when phosphorylated at S311.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human STK39 around the phosphorylation site of Ser311. AA range:277-326
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- STK39 (serine threonine Kinase 39 (STK39))
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别名
- STK39
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背景
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Synonyms: STK39, SPAK, STE20/SPS1-related proline-alanine-rich protein kinase, Ste-20-related kinase, DCHT, Serine/threonine-protein kinase 39
Background: This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. [provided by RefSeq, Jul 2008],
Gene Name: STK39
Protein Name: STE20/SPS1-related proline-alanine-rich protein kinase
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分子量
- 59 kDa
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基因ID
- 27347
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OMIM
- 607648
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UniProt
- Q9UEW8
抗原
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