PLK1 抗体 (pSer137)
Our Local Distributor
北京 101111
Quick Overview for PLK1 抗体 (pSer137) (ABIN1450452)
抗原
See all PLK1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 103-152, pSer137
-
原理
- Plk1 (phospho Ser137) Antibody
-
特异性
- Phospho-Plk1 (S137) Polyclonal Antibody detects endogenous levels of Plk1 protein only when phosphorylated at S137.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- The antiserum was produced against synthesized peptide derived from human PLK1 around the phosphorylation site of Ser137. AA range:103-152
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500-2000, IF ICC 1:50-200,ELISA 1:2000-20000,IHC 1:50-200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- PLK1 (Polo-Like Kinase 1 (PLK1))
-
别名
- PLK1
-
背景
-
Synonyms: PLK1, PLK, Serine/threonine-protein kinase PLK1, Polo-like kinase 1, PLK-1, Serine/threonine-protein kinase 13, STPK13
Background: The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis, hence, it is a target for cancer therapy. [provided by RefSeq, Sep 2015],
Gene Name: PLK1
Protein Name: Serine/threonine-protein kinase PLK1
-
分子量
- 68 kDa
-
基因ID
- 5347
-
OMIM
- 602098
-
UniProt
- P53350
-
途径
- Cell Division Cycle, M Phase
抗原
-