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GFRA1 抗体

This anti-GFRA1 antibody is a 小鸡 多克隆 antibody detecting GFRA1 in WB, ELISA 和 IF. Suitable for 人.
产品编号 ABIN1450224
发货至: 中国

Quick Overview for GFRA1 抗体 (ABIN1450224)

抗原

See all GFRA1 抗体
GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))

适用

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宿主

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小鸡

克隆类型

  • 62
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多克隆

标记

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This GFRA1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • 特异性

    Glial cell line-derived neurotrophic factor (GDNF) andneurturin (NTN) are two structurally related, potent neurotrophic factors thatplay key roles in the control of neuron survival and differentiation. The GFRa-1is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediatesactivation of the RET tyrosine kinase receptor (www.ncbi.nlm.nih.gov/gene/2674)

    产品特性

    Mono- and polyclonal antibodies to human growth factors and neural growth factor receptors.

    纯化方法

    GFRa-1 affinity purified

    亚型

    IgY
  • 应用备注

    Westernimmunoblotting, recommended dilution 1:5 000 to 1:10 000, ELISA: 1:80 000 to160 000,IF 1:1000 to 1:2000. Polyclonal antibody working titer has to be established practically for each particularantigen and assay format

    说明

    Synonym: RET ligand 1, TGF-beta related neurotrophic factorreceptor 1

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/ml

    缓冲液

    Concentrated ammonium sulphate in PBS pH 7.4

    注意事项

    As product is (NH4)2SO4 precipitate, mix well by pipetting or vortexing prior use

    储存条件

    4 °C

    储存方法

    This product is shipped in non-frozen liquid form in ambient conditions
  • 抗原

    GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))

    别名

    GFRa-1

    背景

    Recombinant His-tagged human GFRa-1 protein producedusing CHO-based cell line. For production of hGFRa-1, glycosylphosphatidyl-inositol GPI-anchor was removedand protein was secreted to the cell culture supernatant. Protein was purifiedby Ni-affinity chromatography following gel-filtration from cell culturesupernatant

    UniProt

    P56159
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