GFRA1 抗体
Quick Overview for GFRA1 抗体 (ABIN1450224)
抗原
See all GFRA1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Glial cell line-derived neurotrophic factor (GDNF) andneurturin (NTN) are two structurally related, potent neurotrophic factors thatplay key roles in the control of neuron survival and differentiation. The GFRa-1is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediatesactivation of the RET tyrosine kinase receptor (www.ncbi.nlm.nih.gov/gene/2674)
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产品特性
- Mono- and polyclonal antibodies to human growth factors and neural growth factor receptors.
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纯化方法
- GFRa-1 affinity purified
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亚型
- IgY
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应用备注
- Westernimmunoblotting, recommended dilution 1:5 000 to 1:10 000, ELISA: 1:80 000 to160 000,IF 1:1000 to 1:2000. Polyclonal antibody working titer has to be established practically for each particularantigen and assay format
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说明
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Synonym: RET ligand 1, TGF-beta related neurotrophic factorreceptor 1
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/ml
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缓冲液
- Concentrated ammonium sulphate in PBS pH 7.4
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注意事项
- As product is (NH4)2SO4 precipitate, mix well by pipetting or vortexing prior use
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储存条件
- 4 °C
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储存方法
- This product is shipped in non-frozen liquid form in ambient conditions
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- GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))
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别名
- GFRa-1
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背景
- Recombinant His-tagged human GFRa-1 protein producedusing CHO-based cell line. For production of hGFRa-1, glycosylphosphatidyl-inositol GPI-anchor was removedand protein was secreted to the cell culture supernatant. Protein was purifiedby Ni-affinity chromatography following gel-filtration from cell culturesupernatant
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UniProt
- P56159
抗原
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