HHATL 抗体 (N-Term)
This anti-HHATL antibody is a 兔 多克隆 antibody detecting HHATL in WB, IHC (p), IF 和 EIA. Suitable for 人, 小鼠 和 大鼠.
Quick Overview for HHATL 抗体 (N-Term) (ABIN1450142)
抗原
See all HHATL 抗体
HHATL
(Hedgehog Acyltransferase-Like (HHATL))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This HHATL antibody is un-conjugated
应用范围
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
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抗原表位
- N-Term
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 19 amino acid synthetic peptide near the amino terminus of Human HHATL
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- HHATL (Hedgehog Acyltransferase-Like (HHATL))
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别名
- GUP1 / HHATL
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背景
- The Protein-cysteine N-palmitoyltransferase HHAT-like protein (HHATL), also known at the mammalian glycerol uptake/transporter 1 (Gup1) is a homolog of the S. cerevisiae Gup1. It is an endoplasmic reticulum (ER) membrane protein that co-localizes with the mammalian hedgehog acyltransferse Skn and interferes with its N-terminal palmitoylation of Sonic hedgehog (SHH), suggesting that HHATL acts as a negative regulator for N-terminal palmitoylation of SHH. HHATL is highly expressed in normal skin, but becomes down-regulated in skin squamous cell carcinoma, suggesting it may play a role in its development .Synonyms: C3orf3, Glycerol uptake/transporter homolog, Hedgehog acyltransferase-like protein, KIAA1173, Protein-cysteine N-palmitoyltransferase HHAT-like protein
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基因ID
- 57467
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NCBI登录号
- NP_065758
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途径
- Hedgehog Signaling
抗原
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