NKX2-1 抗体 (N-Term)
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Quick Overview for NKX2-1 抗体 (N-Term) (ABIN1450126)
抗原
See all NKX2-1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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交叉反应 (详细)
- Species reactivity (tested):Human, Mouse, Rat.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 16 amino acid synthetic peptide near the amino terminus of Human NKX2-1
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- NKX2-1 (NK2 Homeobox 1 (NKX2-1))
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别名
- TTF1 / NKX2A
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背景
- NKX2-1 (NK2 homeobox 1) has been identified as a thyroid-specific transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin and thyrotropin receptor. NKX2-1 is crucial in the maintenance of the thyroid differentiation phenotype and morphogenesis. It contains one homeobox DNA-binding domain. NKX2-1 also may play a role in lung development and surfactant homeostasis. Mutations and deletions in this gene are associated with benign hereditary chorea, congenital hypothyroidism, neonatal respiratory distress, and may be associated with thyroid cancer. NKX2-1 has been suggested to be a candidate suppressor of malignant progression.Synonyms: Homeobox protein NK-2 homolog A, Homeobox protein Nkx-2.1, NKX2-1, Nkx-2.1, TITF1, TTF-1, Thyroid nuclear factor 1, Thyroid transcription factor 1
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基因ID
- 7080
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UniProt
- P43699
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Glucan Metabolic Process, Feeding Behaviour
抗原
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