GRB10 抗体 (C-Term)
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Quick Overview for GRB10 抗体 (C-Term) (ABIN1450124)
抗原
See all GRB10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- Affinity Chromatography purified via peptide column
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免疫原
- 17 amino acid synthetic peptide near the carboxy terminus of Human GRB10
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- GRB10 (Growth Factor Receptor-Bound Protein 10 (GRB10))
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别名
- GRB10 / GRBIR
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背景
- GRB10 belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules and function in diverse cellular processes. GRB10 is a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of GRB10 inhibits tyrosine kinase activity and results in growth suppression. GRB10 can also interact with the L isoform of the proapoptotic protein Bim. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts .Synonyms: Grb-IR, Growth factor receptor-bound protein 10, Insulin receptor-binding protein Grb-IR, KIAA0207
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基因ID
- 2887
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NCBI登录号
- NP_005302
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途径
- Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2
抗原
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