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Kdm6b 抗体 (N-Term)

This anti-Kdm6b antibody is a 兔 多克隆 antibody detecting Kdm6b in WB, IF 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1450111
发货至: 中国

Quick Overview for Kdm6b 抗体 (N-Term) (ABIN1450111)

抗原

See all Kdm6b 抗体
Kdm6b (Lysine (K)-Specific Demethylase 6B (Kdm6b))

适用

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  • 24
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  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 48
  • 1
  • 1

克隆类型

  • 49
  • 1
多克隆

标记

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  • 4
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  • 1
  • 1
  • 1
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  • 1
  • 1
  • 1
This Kdm6b antibody is un-conjugated

应用范围

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  • 11
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  • 1
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 8
    • 7
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    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
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    • 1
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    • 1
    • 1
    • 1
    • 1
    N-Term

    交叉反应 (详细)

    Species reactivity (tested):Human, Mouse, Rat.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    16 amino acid synthetic peptide from near the amino terminus of Human JMJD3

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Kdm6b (Lysine (K)-Specific Demethylase 6B (Kdm6b))

    别名

    JMJD3 / KDM6B

    背景

    The Jumonji domain-containing protein 3 (JMJD3) functions as a trimethylation-specific demethylase, converting the trimethylated histone H3 Lys27 residue to the dimethylated form, and is thought to also function as a transcriptional repressor. JMJD3 plays a central role in regulation of posterior development, by regulating HOX gene expression. It is involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation. JMJD3 can also interact with and demethylate p53, resulting in its stabilization and localization to the nucleus in mouse embryo fibroblasts during neural stem cell differentiation.Synonyms: Histone demethylase JMJD3, JmjC domain-containing protein 3, Jumonji domain-containing protein 3, KIAA0346, Lysine demethylase 6B

    基因ID

    23135

    途径

    Warburg Effect
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