PRICKLE1 抗体 (C-Term)
This 兔 多克隆 anti-PRICKLE1 antibody specifically detects PRICKLE1 in WB, IF 和 EIA. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN1450074
发货至:
中国
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Quick Overview for PRICKLE1 抗体 (C-Term) (ABIN1450074)
抗原
See all PRICKLE1 抗体
PRICKLE1
(Prickle-Like Protein 1 (PRICKLE1))
适用
人, 大鼠, 小鼠
宿主
兔
克隆类型
多克隆
标记
This PRICKLE1 antibody is un-conjugated
应用范围
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
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抗原表位
- C-Term
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse, Rat.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 19 amino acid synthetic peptide near the carboxy terminus of human PRICKLE1
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亚型
- IgG
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anti-Prickle-Like Protein 1 (PRICKLE1) (AA 684-756) antibody
PRICKLE1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 8G5 unconjugated
anti-Prickle-Like Protein 1 (PRICKLE1) (AA 684-756) antibodyPRICKLE1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PRICKLE1 (Prickle-Like Protein 1 (PRICKLE1))
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别名
- PRICKLE1
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背景
- PRICKLE1, also known as RILP or EPM1B, is a Disheveled-associated protein that serves as a nuclear translocation receptor for REST/NRSF and REST4 (1, 2). It contains three N-terminal LIM domains and three C-terminal nuclear localization signals. It localizes to the cytoplasm, as well as to the nuclear membrane and expressed at higher levels in placenta. PRICKLE1 is a negative regulator of the Wnt / beta-catenin signaling pathway and is a putative tumor suppressor in human HCCs. Defects in the gene encoding PRICKLE1 are associated with autosomal recessive progressive myoclonic epilepsy.Synonyms: PRICKLE-1, Prickle-like protein 1, REST/NRSF-interacting LIM domain protein 1, RILP
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基因ID
- 144165
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NCBI登录号
- NP_694571
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途径
- WNT signaling, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development, Protein targeting to Nucleus
抗原
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