C2orf40 抗体 (C-Term)
Quick Overview for C2orf40 抗体 (C-Term) (ABIN1450064)
抗原
See all C2orf40 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
交叉反应 （详细）
- Species reactivity (tested):Human, Mouse, Rat.
-
纯化方法
- Affinity chromatography purified via peptide column
-
免疫原
- 20 amino acid synthetic peptide near the carboxy terminus of Human ECRG4
-
亚型
- IgG
-
-
anti-Chromosome 2 Open Reading Frame 40 (C2orf40) (AA 32-148) antibody
C2orf40 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Chromosome 2 Open Reading Frame 40 (C2orf40) (C-Term) antibodyC2orf40 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chromosome 2 Open Reading Frame 40 (C2orf40) antibodyC2orf40 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chromosome 2 Open Reading Frame 40 (C2orf40) (AA 41-90) antibodyC2orf40 适用: 人, 小鼠 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- C2orf40 (Chromosome 2 Open Reading Frame 40 (C2orf40))
-
别名
- Augurin
-
背景
- The esophageal cancer-related gene 4 (ECRG4), also known as Augurin, was identified through differential display screening between esophageal cancer and normal tissue. Hypermethylation of CpG sites in the ECRG4 promoter correlate with ECRG4 downregulation in numerous esophageal squamous cell carcinoma tissues.. In transfected cells, overexpression of ECRG4 induced G1 arrest, dephosphorylation of Rb and decreased expression of cyclins D1 and D3. Increased expression of ECRG4 in aged mouse brain is observed compared with young mouse brain. The increased ECRG4 level was accompanied by elevated senescence-associated acidic beta-galactosidase activity, suggesting that ECRG4 is involved in cellular differentiation and senescence.Synonyms: C2orf40, ECRG4
-
基因ID
- 84417
抗原
-
