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CHD7 抗体 (N-Term)

This anti-CHD7 antibody is a 兔 多克隆 antibody detecting CHD7 in WB, IHC (p), IF 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN1450043
发货至: 中国

Quick Overview for CHD7 抗体 (N-Term) (ABIN1450043)

抗原

See all CHD7 抗体
CHD7 (Chromodomain Helicase DNA Binding Protein 7 (CHD7))

适用

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人, 小鼠

宿主

  • 7
  • 1
  • 1

克隆类型

  • 9
多克隆

标记

  • 9
This CHD7 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    交叉反应 (详细)

    Species reactivity (tested):Human, Mouse.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    CHD7 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human CHD7

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CHD7 (Chromodomain Helicase DNA Binding Protein 7 (CHD7))

    别名

    CHD7

    背景

    CHD proteins belong to a superfamily of proteins of ATP-dependent chromatin remodeling enzymes that have a unique combination of functional domains, including two N-terminal chromodomains, a SNF2-like ATPase/helicase domain and a DNA-binding domain. These proteins are thought to play a role in early embryonic development by affecting chromatin structure and gene expression. Mutations in one member of this family, CHD7, result in CHARGE syndrome. It colocalizes with embryonic stem (ES) cell master regulators OCT4/POU5F1, SOX2, and NANOG and is thought to modulate ES-specific gene transcription. Together with SOX2, CHD7 has been suggested to also regulate several human disease genes.Synonyms: ATP-dependent helicase CHD7, CHD-7, Chromodomain-helicase-DNA-binding protein 7, KIAA1416

    基因ID

    55636

    UniProt

    Q9P2D1

    途径

    Sensory Perception of Sound, Chromatin Binding
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