CHD7 抗体 (N-Term)
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Quick Overview for CHD7 抗体 (N-Term) (ABIN1450043)
抗原
See all CHD7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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交叉反应 (详细)
- Species reactivity (tested):Human, Mouse.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- CHD7 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human CHD7
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CHD7 (Chromodomain Helicase DNA Binding Protein 7 (CHD7))
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别名
- CHD7
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背景
- CHD proteins belong to a superfamily of proteins of ATP-dependent chromatin remodeling enzymes that have a unique combination of functional domains, including two N-terminal chromodomains, a SNF2-like ATPase/helicase domain and a DNA-binding domain. These proteins are thought to play a role in early embryonic development by affecting chromatin structure and gene expression. Mutations in one member of this family, CHD7, result in CHARGE syndrome. It colocalizes with embryonic stem (ES) cell master regulators OCT4/POU5F1, SOX2, and NANOG and is thought to modulate ES-specific gene transcription. Together with SOX2, CHD7 has been suggested to also regulate several human disease genes.Synonyms: ATP-dependent helicase CHD7, CHD-7, Chromodomain-helicase-DNA-binding protein 7, KIAA1416
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基因ID
- 55636
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UniProt
- Q9P2D1
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途径
- Sensory Perception of Sound, Chromatin Binding
抗原
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