TOX 抗体 (N-Term)
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北京 101111
Quick Overview for TOX 抗体 (N-Term) (ABIN1449998)
抗原
See all TOX 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- A 17 amino acid synthetic peptide near the amino terminus of Human TOX
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亚型
- IgG
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anti-Thymus High Mobility Group Box Protein (TOX) (AA 141-288) antibody
TOX 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Thymus High Mobility Group Box Protein (TOX) (N-Term) antibodyTOX 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Thymus High Mobility Group Box Protein (TOX) antibodyTOX 适用: 小鼠, 大鼠 IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Thymus High Mobility Group Box Protein (TOX) (N-Term) antibodyTOX 适用: 人, 小鼠, 大鼠, 犬, Cow, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Thymus High Mobility Group Box Protein (TOX) (N-Term) antibodyTOX 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- TOX (Thymus High Mobility Group Box Protein (TOX))
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别名
- TOX
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背景
- TOX (thymocyte selection-associated high mobility group (HMG) box protein) is a member of the HMG box family of DNA-binding proteins and likely plays a role in the regulation of T-cell development (1,2). It is a 526 amino acid nuclear protein and the expression of TOX is upregulated by pre-T cell receptor (pre-TCR) and TCR activation in immature thymocytes. TOX-mediated positive selection is associated with up-regulation of RUNX3 and is calcineurin dependent. TOX-dependent transition to the CD4+CD8 stage is required for development of class II major histocompatibility complex-specific T cells.Synonyms: KIAA0808, Thymocyte selection-associated high mobility group box protein TOX, Thymus high mobility group box protein TOX
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分子量
- 58 kDa
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基因ID
- 9760
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NCBI登录号
- NP_055544
抗原
-
