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TOX 抗体 (N-Term)

TOX 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6991735
发货至: 中国
  • 抗原 See all TOX 抗体
    TOX (Thymus High Mobility Group Box Protein (TOX))
    抗原表位
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    AA 130-180, N-Term
    适用
    • 16
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 17
    克隆类型
    • 16
    • 1
    多克隆
    标记
    • 13
    • 2
    • 1
    • 1
    This TOX antibody is un-conjugated
    应用范围
    • 11
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    特异性
    No alternatively spliced transcript variants have been observed.
    纯化方法
    TOX Antibody is affinity chromatography purified via peptide column.
    免疫原
    TOX antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human TOX. The immunogen is located within amino acids 130 - 180 of TOX.
    亚型
    IgG
    Top Product
    Discover our top product TOX Primary Antibody
  • 应用备注
    TOX antibody can be used for detection of TOX by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    TOX Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    TOX antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    TOX (Thymus High Mobility Group Box Protein (TOX))
    别名
    TOX (TOX 产品)
    别名
    TOX1 antibody, 1700007F02Rik antibody, thymocyte selection associated high mobility group box antibody, thymocyte selection-associated high mobility group box antibody, TOX antibody, Tox antibody
    背景
    TOX Antibody: TOX (thymocyte selection-associated high mobility group (HMG) box protein) is a member of the HMG box family of DNA-binding proteins and likely plays a role in the regulation of T-cell development. It is a 526 amino acid nuclear protein and the expression of TOX is upregulated by pre-T cell receptor (pre-TCR) and TCR activation in immature thymocytes. TOX-mediated positive selection is associated with up-regulation of RUNX3 and is calcineurin dependent. TOX-dependent transition to the CD4+CD8 stage is required for development of class II major histocompatibility complex-specific T cells.
    分子量
    58 kDa
    基因ID
    9760
    NCBI登录号
    NP_055544
    UniProt
    O94900
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