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FLT3 抗体 (N-Term)

FLT3 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1449983
发货至: 中国
  • 抗原 See all FLT3 抗体
    FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
    抗原表位
    • 20
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    N-Term
    适用
    • 157
    • 52
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 159
    • 14
    • 2
    • 1
    克隆类型
    • 160
    • 16
    多克隆
    标记
    • 69
    • 13
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    • 7
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    • 5
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    This FLT3 antibody is un-conjugated
    应用范围
    • 125
    • 69
    • 54
    • 54
    • 31
    • 26
    • 19
    • 14
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    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    18 amino acid synthetic peptide near the center of Human FLT3
    亚型
    IgG
    Top Product
    Discover our top product FLT3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
    别名
    CD135 / FLT3 (FLT3 产品)
    别名
    FLT3 antibody, B230315G04 antibody, CD135 antibody, Flk-2 antibody, Flk2 antibody, Flt-3 antibody, Ly72 antibody, wmfl antibody, FLK-2 antibody, FLK2 antibody, STK1 antibody, fms related tyrosine kinase 3 antibody, FMS-like tyrosine kinase 3 antibody, fms-related tyrosine kinase 3 antibody, FLT3 antibody, Flt3 antibody
    背景
    FLT3 is a member of the class III receptor tyrosine kinase family and its internal tandem duplication (ITD) is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies. It is a membrane bound glycosylated protein that is expressed primarily in early hematopoietic progenitor cells. Upon binding its ligand FL, FLT3 activates multiple signaling pathways including the PI3K/Akt and Ras/MEK/MAPK pathways. In cells expressing FLT3-ITD, these pathways are constitutively on, resulting in abnormal cell growth and anti-apoptotic activity.Synonyms: FL cytokine receptor, STK1, Stem cell tyrosine kinase 1, Tyrosine-protein kinase receptor FLT3
    分子量
    109 kDa
    基因ID
    2322
    NCBI登录号
    NP_004110
    途径
    RTK signaling
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