TAB2 抗体 (C-Term)
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- 抗原 See all TAB2 抗体
- TAB2 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TAB2 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- 14 amino acid synthetic peptide near the carboxy terminus of Human TAB2
- 亚型
- IgG
- Top Product
- Discover our top product TAB2 Primary Antibody
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anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) (N-Term) antibody
TAB2 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) (N-Term) antibodyTAB2 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, Pig, Bat, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) antibodyTAB2 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 3B5 unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) (AA 646-680), (C-Term) antibodyTAB2 适用: 大鼠 WB 宿主: 兔 Polyclonal RB52974 unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) (AA 1-693) antibodyTAB2 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) (AA 1-693) antibodyTAB2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) (Internal Region) antibodyTAB2 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) (AA 350-693) antibodyTAB2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- TAB2 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2))
- 别名
- TAB2 / MAP3K7IP2 (TAB2 产品)
- 别名
- CHTD2 antibody, MAP3K7IP2 antibody, 1110030N06Rik antibody, A530078N03Rik antibody, Map3k7ip2 antibody, mKIAA0733 antibody, map3k7ip2 antibody, zgc:77446 antibody, TGF-beta activated kinase 1/MAP3K7 binding protein 2 antibody, TAB2 antibody, Tab2 antibody, tab2 antibody
- 背景
- TAB2 is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation NF-kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKL through the activation of the receptor activator of NF-kappaB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. Recent experiments have shown that TAB2 and the related protein TAB3 constitutitvely interact with the autophagy mediator Beclin-1, upon induction of autophagy, these proteins dissociate from Beclin-1 and bind TAK1. Overexpression of TAB2 and TAB3 inhibit autophagy, while their depletion triggers it, suggesting that TAB2 and TAB3 act as a control point for autophagy.Synonyms: Mitogen-activated protein kinase kinase kinase 7-interacting protein 2, TAK1-binding protein 2, Tab-2
- 基因ID
- 23118
- NCBI登录号
- NP_055908
- 途径
- TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Ubiquitin Proteasome Pathway
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