DISP2 抗体 (N-Term)
This 兔 多克隆 antibody specifically detects DISP2 in IHC (p) 和 EIA. It exhibits reactivity toward 人.
产品编号 ABIN1449961
发货至:
中国
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Quick Overview for DISP2 抗体 (N-Term) (ABIN1449961)
抗原
See all DISP2 抗体
DISP2
(Dispatched Homolog 2 (DISP2))
适用
人
宿主
兔
克隆类型
多克隆
标记
This DISP2 antibody is un-conjugated
应用范围
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
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抗原表位
- N-Term
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 18 amino acid synthetic peptide near the amino terminus of Human DISP2
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亚型
- IgG
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anti-Dispatched Homolog 2 (DISP2) (AA 1101-1200) antibody
DISP2 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- DISP2 (Dispatched Homolog 2 (DISP2))
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别名
- DISP2 / DISPB
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背景
- DISP2 is the second of three known homologs of the D. melanogaster protein Dispatched. It is a multi-transmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored Hedgehog from producing cells. Hedgehog is a major player in signaling pathways during embryogenesis, tissue regeneration, and carcinogenesis and the DISP proteins have been implicated in these pathways. Recently, it has been shown that DISP2 is translationally regulated by the microRNA miR-214 in zebrafish. Expression of this miRNA decreased DISP2 promoter activity in vitro and its overexpression in zebrafish resulted in a phenotype identical to that observed by DISP2 mutants.Synonyms: KIAA1742, Protein dispatched homolog 2
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基因ID
- 85455
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UniProt
- A7MBM2
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途径
- Hedgehog Signaling
抗原
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