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TTBK2 抗体 (C-Term)

This anti-TTBK2 antibody is a 兔 多克隆 antibody detecting TTBK2 in IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN1449960
发货至: 中国

Quick Overview for TTBK2 抗体 (C-Term) (ABIN1449960)

抗原

See all TTBK2 抗体
TTBK2 (tau Tubulin Kinase 2 (TTBK2))

适用

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宿主

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克隆类型

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多克隆

标记

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This TTBK2 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    C-Term

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    18 amino acid synthetic peptide near the carboxy terminus of Human TTBK2

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    TTBK2 (tau Tubulin Kinase 2 (TTBK2))

    别名

    TTBK2

    背景

    Tau tubulin kinase (TTBK2) is a serine/threonine kinase whose substrates are thought to include the tau and tubulin proteins. Mutations in the TTBK2 gene cause spinocerebellar ataxia type 11 (SCA11), a neurodegenerative disease characterized by progressive ataxia and atrophy of the cerebellum and brainstem. Recent studies have shown that increased levels of TTBK2 expression in kidney carcinoma and melanoma cell lines increases resistance to the chemotherapeutic agent Sunitinib, and that reduction of TTBK2 though the use of siRNA sensitized these cell lines to the effects of Sunitib, suggesting that TTBK2 can be used as a resistance marker as well a potential target to overcome resistance.Synonyms: KIAA0847, Tau-tubulin kinase 2

    基因ID

    146057
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