WDR35 抗体 (N-Term)
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北京 101111
Quick Overview for WDR35 抗体 (N-Term) (ABIN1449959)
抗原
See all WDR35 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 16 amino acid synthetic peptide near the amino terminus of Human WDR35
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亚型
- IgG
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anti-WD Repeat Domain 35 (WDR35) (AA 954-1181) antibody
WDR35 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-WD Repeat Domain 35 (WDR35) (AA 71-120) antibodyWDR35 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-WD Repeat Domain 35 (WDR35) (N-Term) antibodyWDR35 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-WD Repeat Domain 35 (WDR35) (N-Term) antibodyWDR35 适用: 人, 犬, 豚鼠, 马, 小鼠, 兔, 大鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- WDR35 (WD Repeat Domain 35 (WDR35))
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别名
- WDR35
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背景
- WD40 repeats are a common structural module in eukaryotic proteins, and proteins containing WD40 domains have a wide range of functions, including signal transduction, cell cycle regulation, RNA splicing, and transcription. One such protein, WDR35, also known as CED2, has been shown to be mutated in patients with Sensenbrenner syndrome/cranioectodermal dysplasia (CED), an autosomal-recessive disease that is characterized by craniosynstosis and ectodermal and skeletal abnormalities. WDR35 localizes to cilia and dentrosomes during embryogenesis and human and mouse fibroblasts that lack this gene fail to produce cilia. Mutations in this gene can also cause short-rib polydactyly syndromes due to abnormal ciliogenesis.Synonyms: IFT121, Intraflagellar transport protein 121 homolog, KIAA1336, WD repeat-containing protein 35
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基因ID
- 57539
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NCBI登录号
- NP_001006658
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途径
- Hedgehog Signaling
抗原
-
