Centriolin 抗体 (C-Term)
Quick Overview for Centriolin 抗体 (C-Term) (ABIN1449934)
抗原
See all Centriolin (CNTRL) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse, Rat.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 17 amino acid synthetic peptide near the carboxy terminus of Human CCP110
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亚型
- IgG
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anti-Centriolin (CNTRL) antibody
CNTRL 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Centriolin (CNTRL) (AA 2101-2325) antibodyCNTRL 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Centriolin (CNTRL) (AA 250-500) antibodyCNTRL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Centriolin (CNTRL) (C-Term) antibodyCNTRL 适用: 人, 猴 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Centriolin (CNTRL)
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别名
- CEP110
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背景
- CCP110 is a centrosomal protein required for the centrosome to function as a microtubule organizing center and plays an essential role in centrosome duplication. It is a target of cyclin-dependent kinases (CDKs), disruption of CCP110 phosphorylation leads to unscheduled centrosome separation and polyploidy. CCP110 is also a target of SCF (Cyclin F) ubiquitin ligase complex, leading to its degradation, suggesting that this complex controls centrosome homeostasis and mitotic fidelity through CCP110 degradation. The centriolar kinesin Kif24 also interacts with CP110 and remodel microtubules and regulate ciliogenesis.Synonyms: CP110, Centrosomal protein of 110 kDa, KIAA0419
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基因ID
- 9738
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NCBI登录号
- NP_001185951
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途径
- M Phase, SARS-CoV-2 Protein Interactome
抗原
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