ATG7 抗体 (AA 501-531)
Quick Overview for ATG7 抗体 (AA 501-531) (ABIN1449607)
抗原
See all ATG7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 501-531
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纯化方法
- Saturated Ammonium Sulfate precipitation followed by dialysis against PBS
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免疫原
- KLH conjugated synthetic peptide between 501~531 amino acids surrounding amino acid R509 of Human APG7L Genename: ATG7
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亚型
- Ig Fraction
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anti-ATG7 Autophagy Related 7 (ATG7) (AA 500-676) antibody
ATG7 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ATG7 Autophagy Related 7 (ATG7) (AA 477-698) antibodyATG7 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-ATG7 Autophagy Related 7 (ATG7) (AA 540-569), (C-Term) antibodyATG7 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB7474 unconjugated
anti-ATG7 Autophagy Related 7 (ATG7) (AA 22-51) antibodyATG7 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ATG7 Autophagy Related 7 (ATG7) (AA 494-523) antibodyATG7 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-ATG7 Autophagy Related 7 (ATG7) antibodyATG7 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-ATG7 Autophagy Related 7 (ATG7) (AA 558-703) antibodyATG7 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7D3E5 unconjugated
anti-ATG7 Autophagy Related 7 (ATG7) (N-Term) antibodyATG7 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-ATG7 Autophagy Related 7 (ATG7) (N-Term) antibody (HRP)ATG7 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal HRP
anti-ATG7 Autophagy Related 7 (ATG7) (N-Term) antibody (FITC)ATG7 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal FITC
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- ATG7 (ATG7 Autophagy Related 7 (ATG7))
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别名
- APG7L / ATG7
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背景
- Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG7 functions as an E1 enzyme essential for multisubstrates such as GABARAPL1 and ATG12. APG3L is an E2-like conjugating enzyme facilitating covalent binding of APG8 (MAP1LC3) to phosphatidylethanolamine (PE). APG7 (an E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with APG3. Formation of the PE conjugate is essential for autophagy.Synonyms: APG7-like, Autophagy-related protein 7, Ubiquitin-activating enzyme E1-like protein
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分子量
- 77960 Da
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基因ID
- 10533
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NCBI登录号
- NP_001129503
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途径
- Response to Water Deprivation, Autophagy
抗原
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