CDKN2B 抗体
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北京 101111
Quick Overview for CDKN2B 抗体 (ABIN1449282)
抗原
See all CDKN2B 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody reacts with p15INK4b (15 kDa).
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交叉反应 (详细)
- Species reactivity (tested):Human (HeLa, 293T, transfectant), does not react with Mouse (NIH/3T3, P3U1) and Rat (PC12, Rat1)
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纯化方法
- Protein A agarose
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免疫原
- GST-full length human p15INK4b
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 50 % glycerol, pH 7.2. Contains no preservatives.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Upon receipt, store (in aliqouts) at -20 °C.
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- CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))
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别名
- CDKN2B / p15INK4b
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背景
- Progression through the G1 phase of the cell cycle is regulated in part by the D-type cyclin-dependent kinases, cdk4 and cdk6. p15INK4b is a specific inhibitor of cdk4/cdk6 and is periodically expressed during cell cycle. Induction of p15INK4b is important for TGFß-mediated cytostasis in epithelial cells but not in hematopoietic cells, it may act as an effector of TGF-ß mediated cell arrest.Synonyms: Cyclin-dependent kinase 4 inhibitor B, MTS2, Multiple tumor suppressor 2, p14-INK4b, p14INK4b, p15-INK4b
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基因ID
- 1030
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NCBI登录号
- NP_004927
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UniProt
- P42772
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases
抗原
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