14-3-3 gamma 抗体 (N-Term)
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Quick Overview for 14-3-3 gamma 抗体 (N-Term) (ABIN1449274)
抗原
See all 14-3-3 gamma (YWHAG1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-12, N-Term
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特异性
- This antibody reacts with 14-3-3γ, which the N-terminal Met is removed as a result of acetylated the N-terminal Val, on Western blotting. This antibody does not recognize unprocessed (non-modified) 14-3-3γ.
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交叉反应 (详细)
- Species reactivity (tested):Human, Mouse, Rat
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纯化方法
- Protein A agarose
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免疫原
- KLH-conjugated human 14-3-3gamma N-terminal peptides (1-12 aa)
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亚型
- IgG2a
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Upon receipt, store (in aliqouts) at -20 °C.
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- 14-3-3 gamma (YWHAG1)
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别名
- 14-3-3 Protein gamma
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背景
- The 14-3-3 protein family comprises critical regulatory molecules involved in signaling during cell division, proliferation, and apoptosis. 14-3-3 γ, a subtype of the 14-3-3 family of proteins, was thought to be brain- and neuron-specific. However, 14-3-3 γ was not neuron-specific but also expressed in astrocytes. Endogenous 14-3-3 γ proteins in immature astrocytes appeared filamentous and co-localized with filamentous actin (F-actin). And, 14-3-3 γ proteins play a role in cytoskeletal function during the process of cell division and apoptosis in astrocytes in association with actin. This expression is induced in arterial trauma by cytokines, and suggests that this protein may play an important role in progression of vascular proliferative diseases.Synonyms: KCIP-1, Protein kinase C inhibitor protein 1, YWHAG
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分子量
- 33 kDa
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基因ID
- 7532
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NCBI登录号
- NP_036611
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UniProt
- P61981
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途径
- Myometrial Relaxation and Contraction, M Phase
抗原
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