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14-3-3 gamma 抗体 (N-Term)

This anti-14-3-3 gamma antibody is a 小鼠 单克隆 antibody detecting 14-3-3 gamma in WB 和 IP. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1449274
发货至: 中国

Quick Overview for 14-3-3 gamma 抗体 (N-Term) (ABIN1449274)

抗原

See all 14-3-3 gamma (YWHAG1) 抗体
14-3-3 gamma (YWHAG1)

适用

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人, 小鼠, 大鼠

宿主

  • 73
  • 9
小鼠

克隆类型

  • 61
  • 21
单克隆

标记

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This 14-3-3 gamma antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP)

克隆位点

KC21
  • 抗原表位

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    AA 1-12, N-Term

    特异性

    This antibody reacts with 14-3-3γ, which the N-terminal Met is removed as a result of acetylated the N-terminal Val, on Western blotting. This antibody does not recognize unprocessed (non-modified) 14-3-3γ.

    交叉反应 (详细)

    Species reactivity (tested):Human, Mouse, Rat

    纯化方法

    Protein A agarose

    免疫原

    KLH-conjugated human 14-3-3gamma N-terminal peptides (1-12 aa)

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

    储存液

    Without preservative

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Upon receipt, store (in aliqouts) at -20 °C.
  • 抗原

    14-3-3 gamma (YWHAG1)

    别名

    14-3-3 Protein gamma

    背景

    The 14-3-3 protein family comprises critical regulatory molecules involved in signaling during cell division, proliferation, and apoptosis. 14-3-3 γ, a subtype of the 14-3-3 family of proteins, was thought to be brain- and neuron-specific. However, 14-3-3 γ was not neuron-specific but also expressed in astrocytes. Endogenous 14-3-3 γ proteins in immature astrocytes appeared filamentous and co-localized with filamentous actin (F-actin). And, 14-3-3 γ proteins play a role in cytoskeletal function during the process of cell division and apoptosis in astrocytes in association with actin. This expression is induced in arterial trauma by cytokines, and suggests that this protein may play an important role in progression of vascular proliferative diseases.Synonyms: KCIP-1, Protein kinase C inhibitor protein 1, YWHAG

    分子量

    33 kDa

    基因ID

    7532

    NCBI登录号

    NP_036611

    UniProt

    P61981

    途径

    Myometrial Relaxation and Contraction, M Phase
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