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TLR4 抗体

TLR4 适用: 小鼠 FACS, IP 宿主: 小鼠 Monoclonal UT49 unconjugated
产品编号 ABIN1449233
发货至: 中国
  • 抗原 See all TLR4 抗体
    TLR4 (Toll-Like Receptor 4 (TLR4))
    适用
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    小鼠
    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This TLR4 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunoprecipitation (IP)
    特异性
    This antibody reacts with mouse TLR4 but doesn't react with mouse MD-2 on flow cytometry.
    纯化方法
    Protein A agarose
    免疫原
    Mouse TLR4-MD-2 transfected Ba/F3 cell
    克隆位点
    UT49
    亚型
    IgG2b
    Top Product
    Discover our top product TLR4 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 50 % glycerol, pH 7.2. Contains no preservatives.
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Upon receipt, store (in aliqouts) at -20 °C.
  • 抗原
    TLR4 (Toll-Like Receptor 4 (TLR4))
    别名
    CD284 / TLR4 (TLR4 产品)
    别名
    ARMD10 antibody, CD284 antibody, TLR-4 antibody, TOLL antibody, Lps antibody, Ly87 antibody, Ran/M1 antibody, Rasl2-8 antibody, toll like receptor 4 antibody, toll-like receptor 4 antibody, TLR4 antibody, Tlr4 antibody
    背景
    Toll, a Drosophila receptor molecule with extracellular leucine-rich repeat (LRR), has a role in triggering innate defenses against bacteria or fungi. TLR4 (Toll-like receptor 4) is a member of TLR family, which is human homologue of Toll protein. It has extracellular LRR and an intracellular signaling domain, which is similar to the type I IL-1 receptor. TLR4 is expressed in subpopulations of cells including myeloid cells, B-cells, monocytes, and endothelial cells. Recent studies have suggested that TLR4 might act as a receptor for LPS (lipopolysaccharide). TLR4 alone is not capable of sensing and signaling the presence of LPS, but another molecule MD-2, which is physically associated with TLR4, is required for LPS recognition through TLR4.Synonyms: Toll-like receptor 4
    基因ID
    21898
    NCBI登录号
    NP_067272
    UniProt
    Q9QUK6
    途径
    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins
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