Podoplanin 抗体
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北京 101111
Quick Overview for Podoplanin 抗体 (ABIN1449217)
抗原
See all Podoplanin (PDPN) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody reacts with mouse Aggrus (Podoplanin). The reference 6) described that this antibody does not react to human Aggrus (Podoplanin).
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纯化方法
- Protein G agarose
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免疫原
- NL-17 cell membrane fraction
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亚型
- IgG2a
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Upon receipt, store (in aliqouts) at -20 °C.
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- Podoplanin (PDPN)
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别名
- Podoplanin
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背景
- In addition to hemostasis and host defense, platelets are involved in the induction of inflammation, tissue repair, and tumor metastasis. Aggrus (T1a/Podoplanin) is a novel 36-45 kDa membrane sialoglycoprotein that induces platelet aggregation. Aggrus is highly expressed in various tumor cells and the platelet aggregation ability of Aggrus depends on specific oligosaccharide structures that may be related to the metastasis process in cancer cells. Aggrus has been identified as a diagnostic tumor marker for seminomas and testicular cancers.Synonyms: Aggrus, GP36, Glycoprotein 36, PA2.26 antigen, PDPN, PSEC0003, PSEC0025, T1-alpha
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分子量
- 44 kDa
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基因ID
- 10630
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NCBI登录号
- NP_001006625
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UniProt
- Q86YL7
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途径
- Dicarboxylic Acid Transport
抗原
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